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Lentivirus vector

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AIDS-Related Burkitt Lymphoma, AIDS-Related Diffuse Large B-cell Lymphoma, AIDS-Related Plasmablastic Lymphoma Trial run by the

Active, not recruiting
  • AIDS-Related Burkitt Lymphoma
  • +5 more
  • Bethesda, Maryland
    NCI Lymphoid Malignancies Branch
Jul 31, 2022

AIDS-related Non-Hodgkin Lymphoma, AIDS-related Plasmablastic Lymphoma, AIDS-related Primary Effusion Lymphoma Trial in Duarte

Active, not recruiting
  • AIDS-related Non-Hodgkin Lymphoma
  • +3 more
  • Duarte, California
    City of Hope Medical Center
Feb 17, 2022

X-linked Severe Combined Immunodeficiency (XSCID) Trial run by the National Institute of Allergy and Infectious Diseases (NIAID)

Suspended
  • X-linked Severe Combined Immunodeficiency (XSCID)
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
Aug 24, 2022

HIV Infection, Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Plasmablastic Lymphoma Trial in United States (procedure, drug,

Recruiting
  • HIV Infection
  • +10 more
  • Autologous Hematopoietic Stem Cell Transplantation
  • +7 more
  • La Jolla, California
  • +3 more
Dec 7, 2022

Lymphoma Trial in Duarte (biological, drug, procedure)

Completed
  • Lymphoma
  • lentivirus vector rHIV7-shI-TAR-CCR5RZ-transduced hematopoietic progenitor cells
  • +4 more
  • Duarte, California
    City of Hope Medical Center
Nov 13, 2019

X-Linked Combined Immunodeficiency Diseases Trial run by the NIAID (CD34+ HSCs transduced with the lentivirus vector, VSV-G

Unknown status
  • X-Linked Combined Immunodeficiency Diseases
  • CD34+ HSCs transduced with the lentivirus vector, VSV-G pseudotyped CL20-4i-EF1α-hγc-OPT
  • +2 more
  • Bethesda, Maryland
    Laboratory of Host Defenses (LHD), National Institute of Allergy
Dec 3, 2019

Sickle Cell Disease Trial in Paris (DREPAGLOBE drug product)

Active, not recruiting
  • Sickle Cell Disease
  • DREPAGLOBE drug product
  • Paris, France
    Department of Biotherapy, Necker-Enfants Malades Hospital
Sep 26, 2022

Transfusion Dependent Beta-Thalassemia Trial in Nanning (GMCN-508B (LentiRed))

Recruiting
  • Transfusion Dependent Beta-Thalassemia
  • GMCN-508B (LentiRed)
  • Nanning, Guangxi, China
    The affiliated hospital of guangxi medical university
Feb 28, 2023

Sickle Cell Disease Trial in Boston (Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA

Recruiting
  • Sickle Cell Disease
  • Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA targeting BCL11a
  • Los Angeles, California
  • +8 more
Jan 10, 2023

Metachromatic Leukodystrophy (MLD) Trial in Shenzhen (Lentivirus-mediated delivery of ARSA to the CNS.)

Unknown status
  • Metachromatic Leukodystrophy (MLD)
  • Lentivirus-mediated delivery of ARSA to the CNS.
  • Shenzhen, Guangdong, China
    Lung-Ji Chang
Sep 18, 2019

Solid and Hematological Malignancies Trial in United States (Axicabtagene Ciloleucel, Brexucabtagene Autoleucel, KITE-585)

Enrolling by invitation
  • Solid and Hematological Malignancies
  • Axicabtagene Ciloleucel
  • Brexucabtagene Autoleucel (KTE-X19)
  • Duarte, California
  • +7 more
Jun 29, 2022

Adenosine Deaminase Severe Combined Immune Deficiency Trial (A cryopreserved formulation of autologous mPB CD34+ hematopoietic

Not yet recruiting
  • Adenosine Deaminase Severe Combined Immune Deficiency
  • A cryopreserved formulation of autologous mPB CD34+ hematopoietic stem and progenitor cells transduced ex vivo with the EFS-ADA lentiviral vector encoding the human ADA enzyme
  • (no location specified)
Jun 20, 2022

HIV Trial in Washington (Antiretroviral Therapy Interruption(ATI))

Enrolling by invitation
  • HIV
  • Antiretroviral Therapy Interruption(ATI)
  • Washington, District of Columbia
  • +1 more
Sep 12, 2022

Sickle Cell Disease Trial in Los Angeles, Boston (single infusion of autologous bone marrow derived CD34+ HSC cells transduced

Active, not recruiting
  • Sickle Cell Disease
  • single infusion of autologous bone marrow derived CD34+ HSC cells transduced with the lentiviral vector containing a short-hairpin RNA targeting BCL11a
  • Los Angeles, California
  • +1 more
Feb 8, 2022

Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency Trial in Paris (ARTEGENE drug product)

Not yet recruiting
  • Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency
  • ARTEGENE drug product
  • Paris, France
    Department of Pediatric Immunology, Hematology and Rheumatology
Sep 26, 2022

Lysosomal Storage Disease, Metachromatic Leukodystrophy Trial in Milan (OTL-200 Gene Therapy)

Active, not recruiting
  • Lysosomal Storage Disease
  • Metachromatic Leukodystrophy
  • OTL-200 Gene Therapy
  • Milan, Italy
    Ospedale San Raffaele - Telethon Institute for Gene Therapy (OSR
Nov 4, 2022

Sickle Cell Disease Trial in Los Angeles (ßAS3-FB vector transduced peripheral blood CD34+ cells)

Recruiting
  • Sickle Cell Disease
  • βAS3-FB vector transduced peripheral blood CD34+ cells
  • Los Angeles, California
    University of California, Los Angeles (UCLA)
Apr 9, 2022

P47-Phox, Deficiency of Trial in London (Lentiviral vector transduced CD34+ cells)

Not yet recruiting
  • P47-Phox, Deficiency of
  • Lentiviral vector transduced CD34+ cells
  • London, United Kingdom
    Great Ormond Street Hospital
Aug 2, 2022

Cerebral Adrenoleukodystrophy (CALD) Trial in Worldwide (Lenti-D)

Active, not recruiting
  • Cerebral Adrenoleukodystrophy (CALD)
  • Lenti-D
  • Palo Alto, California
  • +7 more
Mar 22, 2022

Cerebral Adrenoleukodystrophy (CALD) Trial in Worldwide (Lenti-D Drug Product (eli-cel))

Completed
Has Results
  • Cerebral Adrenoleukodystrophy (CALD)
  • Lenti-D Drug Product (eli-cel)
  • Los Angeles, California
  • +7 more
Mar 25, 2022

Lysosomal Storage Diseases, Metachromatic Leukodystrophy Trial in Milan (OTL-200)

Recruiting
  • Lysosomal Storage Diseases
  • Metachromatic Leukodystrophy
  • OTL-200
  • Milan, Italy
    Ospedale San Raffaele - Telethon Institute for Gene Therapy (OSR
Nov 16, 2022

Transfusion-dependent a-Thalassemia Trial (GMCN-508A Drug Product)

Not yet recruiting
  • Transfusion-dependent α-Thalassemia
  • GMCN-508A Drug Product
  • (no location specified)
Feb 24, 2023

Leukemia, Acute Lymphoblastic, Lymphoma, Non-Hodgkin Trial in Ribeirao Preto (CART-19)

Not yet recruiting
  • Leukemia, Acute Lymphoblastic
  • Lymphoma, Non-Hodgkin
  • CART-19
  • Ribeirao Preto, Sao Paulo, Brazil
    Ribeirao Preto School of Medicine, University of Sao Paulo
Oct 23, 2023

Advanced Solid Tumor Trial in Dallas (TCRT-ESO-A2)

Withdrawn
  • Advanced Solid Tumor
  • TCRT-ESO-A2
  • (no location specified)
Aug 31, 2022

MPS-IH (Hurler Syndrome) Trial in Worldwide (Experimental: OTL-203, Active Comparator: Allo-HSCT)

Not yet recruiting
  • MPS-IH (Hurler Syndrome)
  • Experimental: OTL-203
  • Active Comparator: Allo-HSCT
  • Oakland, California
  • +6 more
Nov 27, 2023